Construct Design and Partnered Plasmid Manufacturing
Construct Design for Viral Vector Production
Evaluation, optimization, or full design of your transfer vector constructs ensures that the resulting transfer plasmid includes all the appropriate viral type-specific elements and attributes required for high-titer viral vector production and optimal therapeutic gene expression. Whether utilizing our preferred partners’ proven platforms or working with your specified plasmids, we adapt to your unique requirements, fostering collaboration for mutual success.
Partnered Plasmid Solutions
Genezen is proud to have established preferred partner agreements with industry-leading plasmid partners such as ProBio, Puresyn, and Aldevron. These partnerships enable us to seamlessly manage your viral vector manufacturing program, ensuring a cohesive and integrated approach from preclinical studies through clinical trials. Together, we navigate the complexities of high-quality starting material production to accelerate your path to market by minimizing safety concerns from plasmid backbone. Moreover, we are continually evaluating other plasmid suppliers for quality and quick turnaround to ensure flexibility to our customers.
Genezen routinely procures and stores standard “off-the-shelf” viral vector research-grade plasmids, including Aldevron pALD Lentivirus and AAV packaging plasmid systems that are royalty-free. Using Genezen-supplied plasmids can provide you with a “jump-start” into process development work and research-grade vector production.
Recognizing the unique nature of each therapeutic approach, Genezen retains the flexibility to work with your plasmids or alternative plasmid providers if preferred. Our team’s extensive knowledge and experience empower us to collaborate effectively, ensuring the successful integration of your proprietary plasmids, or preferred provider, into our processes and program management services.
Explore Genezen
Explore Genezen
Lentiviral Vector Production
Accelerating your path through development to commercialization, we deliver high-quality, cost-effective and precise cGMP lentiviral vector manufacturing.
Retroviral Vector Production
We can initiate and maintain reliable supply for your early-phase clinical trials and beyond, delivering high-quality, cost-effective, and precise cGMP master cell bank retroviral vector production and host cell expansion via producer cell lines.
AAV Vector Production
With more than a decade’s worth of experience building diverse AAV platforms, processes, and analytics, our team has the knowledge and skill necessary to bring your program from development to patient.
